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Idiopathic granulomatous hypophysitis: a case report and literature review
Tae Oong Eom, Eun Suk Park , Woo Jae Kim, Sung Ho Park, Min Soo Kim, Soon Chan Kwon, Hong Bo Sim, In Uk Lyo, Jun Bum Park
Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea, Ulsan, Korea
Correspondence  Eun Suk Park ,Tel: (082) 52-250-7139, Fax: (082) 52-250-7138, Email: esparkns@naver.com
Received: May 1, 2018;  Accepted: June 28, 2018.  Published online: June 28, 2018.
ABSTRACT
Idiopathic granulomatous hypophysitis (IGH) is a rare inflammatory disorder of the pituitary that causes transient or permanent gland dysfunction and various neurological symptoms. We present a case involving a 24-year-old woman who was admitted for headache and visual disturbance. The patient was preoperatively diagnosed with pituitary adenoma and underwent transsphenoidal surgery. Histopathology revealed a diagnosis of granulomatous hypophysitis. She was finally diagnosed with IGH given the absence of systemic granulomatous disease. Because IGH is a rare disease and is easily misdiagnosed as other pituitary disease, careful inspection of patient symptoms is required. Surgical intervention provides a histological diagnosis and immediate mass reduction in patients with IGH; however, hormone replacement is frequently required, and long-term follow up is very important.
Key words: granulomatous; hypophysitis, pituitary inflammation; sellar mass
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Idiopathic Granulomatous Hypophysitis: A Case Report and Literature Review  2018 October;4(2)
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